LSD CRYSTAL CAN BE FUN FOR ANYONE

Within the LSD-sure crystal structure, the aspect chain on the lid residue L209EL2 kinds comprehensive hydrophobic contacts with each LSD and encompassing residues in TMs III, IV, and V (Figure 4C). If the lid moved aside to reveal the binding pocket in simulation, numerous of such contacts broke. We thus hypothesized that L209EL2 acts to be a latc